Performance Evaluation of a 3D PSIR Sequence in MRI at 1.5T
Completed
- Conditions
- Multiple Sclerosis
- Registration Number
- NCT04707144
- Lead Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
- Brief Summary
Inclusion visit (D0):
* verification of inclusion and non-inclusion criteria
* information and collection of consent
* standard imaging protocol prescribed as part of the usual treatment: sagittal T1 and T2 slices after injection of contrast product (Gadolinium), o 3D STIR sequence.
* 3D PSIR sequence at the level of the cervical cord for the duration of the additional sequence is 10 minutes, for a total examination time of 45 minutes (instead of 35 minutes).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 106
Inclusion Criteria
- Patient over 18 years old
- To benefit from a medullary exploration planned by MRI 1.5T as part of a first evaluation or a re-evaluation of inflammatory involvement of the nevrax
- Express consent to participate in the study
- Affiliate or beneficiary of a social security scheme
Exclusion Criteria
- Patient benefiting from a legal protection measure
- Pregnant, parturient or breastfeeding woman
- Absolute or relative contraindication to MRI
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measure the intra-observer agreement on the number of lesions detected with the 3D PSIR sequence 1 DAY Estimate the number of active lesions taking the contrast after injection of gadolinium, with the 3D PSIR sequence which is not detected in the set of standard sequences (T1, T2 and STIR) 1 day Compare the diagnostic confidence expressed by the radiologist for the detection of spinal cord injuries with the 3D PSIR sequence compared to the set of standard sequences (T1, T2 and STIR) 1 DAY Measure the signal-to-noise ratio of each of the sequences used (T1, T2, STIR and PSIR) 1 DAY Measure the inter-observer agreement on the number of lesions detected with the 3D PSIR sequence 1 DAY Describe the quality of the images in terms of artifacts for each of the sequences used (T1, T2, STIR and PSIR) 1 DAY Estimate the number of spinal cord injuries detected with the set of standard sequences (T1, T2 and STIR) that are not detected with the 3D PSIR sequence 1 DAY
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (6)
CHU DE Bordeaux
🇫🇷Bordeaux, France
Chu de Clermont-Ferrand
🇫🇷Clermont-ferrand, France
CHU de LYON
🇫🇷Lyon, France
Hôpital privé des Peupliers
🇫🇷Paris, France
Fondation Ophtalmologique Adolphe de Rothschild (FOR)
🇫🇷Paris, France
Chu de Lille
🇫🇷Lille, France