ROLE OF SHODHANA ON PROPERTIES OF KARAVIRA ROOT BARK AND MANAGEMENT OF ECZEMA BY RAKTA KARAVIRA TAILA.
- Conditions
- Atrophic disorder of skin, unspecified,
- Registration Number
- CTRI/2017/06/008823
- Lead Sponsor
- Institute of post graduate teaching and research in Ayurveda
- Brief Summary
An open labelled pilot clinical study was carried out toassess the role of Rakta KaravÄ«ra Taila on patients of VicarcikÄ after gettingapproval of IEC (Ref no: PGT/7/-A/ethics/2015-16/2796;Dated-25/11/2016). The study was registered in CTRI (CTRI/2017/06/008823;Dated-13/06/17). Clinically diagnosed 30cases of VicarcikÄ among the patients visiting the OPD of Dravyaguna departmentwere selected. Test drug was supplied to all the patients weekly for topicalapplication (as per surface area of lesion) for a duration of 4 week (28 days). Weekly assessment was done by self-assessmentquestionnaire and EASI (eczema area and severity index) score parameters.
Among 30 patients, 2 discontinued due to personal reasonsat very begining. In the registered 28 cases who completed the treatment.Statistical analysis was done by applying Unpaired’t’-test for assessing thedifference of pre and post EASI score.
Afterweekly assessment it was found that there was progressive improvement observedin all the considering symptoms of VicarcikÄ like Kaṇdu, PidikÄ, VaivarnyatÄ,DÄha, VedandÄ and Ruká¹£atÄ up to 3rd week of study period. After thatrelief was steady in case of DÄha and VedanÄ, slow improvement in Kaṇdu,VaivurnyatÄ and Ruká¹£atÄ. Decrease in relief in case of PidikÄ was observed on 4thweek.
**Ovar all effect of Therapy:** There was mild tomoderate improvement in the score after treatment as per Äyurvedic parameter aswell as EASI parameters. One patient didn’t show any improvement on the basisof EASI parameters. Overall effect of Therapy on chief complaints like Kaṇdu(Itching) 60.49% relief; Piá¸ikÄ (Pappilae) got 33.33% relief; VaivarṇyatÄ(Discolouration) got 43.90% relief; DÄha (Burning sensation) got 50% relief;VedanÄ (Pain) got 80% relief and Ruká¹£atÄ (Dryness) got 57.32% relief. Effect ofTherapy on EASI parameters like Redness got 42.86% relief; Thickness got 55.56%relief; Scratching got 45.06% relief and Lichenification got 41.67% relief. Noadverse reactions were reported during trail.
1. RaktaKaravÄ«ra Taila, an anubhuta yoga is a fast acting drug against all the assessedsymptoms of VicarcikÄ like Kaṇá¸u, PidikÄ, VaivarnyatÄ, DÄha, VedandÄ and Ruká¹£atÄ.However, rate of improvement was slow down between 3rd and 4thweek, but was still improving instead except in case of PidikÄ.
2. RaktaKaravÄ«ra Taila has a mild to moderate improvement in reducing the symptoms ofVicarcikÄ within 28 days of administration.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
- 1.Classical signs and symptoms of Vicharchika lika Kandu,Pidika,Vaivarna,Daha,Rukhshata,vedana etc.
- 2.Uncomplicated case of Vicharchika.
- 3.Acute case of < 1 year history.
- 1.Suffering with systemic diseases like Diabetes,Hypertension,Malignancy,Tuberculosis,Renal diseases,Liver diseases etc.
- 2.Chronic case of > 1year history.
- 3.Lession of larger surface area.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relief in Itching,Burning sensation,Roughness,Pain etc. 28 days symptoms of Vicharchika. 28 days
- Secondary Outcome Measures
Name Time Method Kandu(Itching),Pidika(Furuncle),Vaivarnata(Discoloration),Daha(Burning sensation),Rukshata(Roughness),Vedana(Pain)etc. up to 28 days
Trial Locations
- Locations (1)
Institute of post graduate teaching and research in Ayurveda
🇮🇳Jamnagar, GUJARAT, India
Institute of post graduate teaching and research in Ayurveda🇮🇳Jamnagar, GUJARAT, IndiaVivek Kumar PatelPrincipal investigator9714486694vivekkmr009@gmail.com