IRCT20220205053945N1Not yet recruitingPhase 3
Evaluation of the effect of probiotic supplements as adjunctive therapy in improving the symptoms of psychosis, anxiety, insomnia and anorexia due to amphetamine and methamphetamine use. A double-blind randomized placebo-controlled clinical trial at Imam Hossein Hospital
Alborz university of medical sciences0 sites50 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 50
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to 60 years (—)
- Sex
- All
Inclusion Criteria
- •Positive amphetamine and methamphetamine test
- •Diagnosis of amphetamine use disorder based on DSM5 criteria after interview with psychiatrist
- •Voluntary organization of the individual and his / her guardian to participate in the project
- •Age: 18 to 60 years old
- •IQ above 70
- •Not receiving to receive electroshock in the last two weeks
- •Do not use other drugs (all opioids, morphine and methadone and marijuana are taken from the patient during the evaluation - testing of urinary toxic acid for amphetamine and methamphetamine)
- •Lack of other psychiatric disorders such as schizophrenia Bipolar disorder Depression with psychosis
Exclusion Criteria
- •Prominent neurological or organic disease and cardiovascular disease and history of cardiac surgery or any cardiovascular procedure, clinical and laboratory examinations and review of family history and records
- •Another diagnosis in Axis I based on DSM-V
- •IQ less than 70 based on clinician clinical suspicion
- •Abusing of other substances (except nicotine and caffeine)
- •Taking oral antipsychotics in the past week or long-acting antipsychotics in the past month
- •Receiving ECT in the last two weeks
- •Women of childbearing age will not be accepted without adequate methods of contraception
- •CHF and liver disease
Investigators
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