Functional Outcomes of Arthroscopic Anterior Cruciate Ligament Reconstruction by Hamstring Graft With and Without Platelet-Rich Plasma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Anterior Drawer's test
研究概览
简要总结
No local data exists regarding the outcomes of anterior cruciate ligament reconstruction by hamstring graft with and without platelet-rich plasma. This study aimed to compare the functional outcomes of arthroscopic anterior cruciate ligament reconstruction by hamstring graft with and without platelet-rich plasma.
详细描述
In animal studies, platelet-rich plasma has shown excellent results in accelerating the healing of the anterior cruciate ligament, but studies on human have shown varying clinical outcomes when investigating platelet-rich plasma for its effects on anterior cruciate ligament reconstruction. The findings of this study could provide important insights about the possible role of platelet-rich plasma in arthroscopic anterior cruciate ligament reconstruction by hamstring graft. to enhance early graft healing and reduce early complications, though its long-term effectiveness remains inconsistent. Studies suggest PRP may improve short-to-medium term outcomes like reduced pain and enhanced knee function,
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any gender
- •Aged 18-40 years
- •With clinically and radiologically confirmed arthroscopic evidence of ACL injury
排除标准
- •With comprised bilateral ACL tears
- •Lack of fitness due to associated comorbidity
- •Fractures of lower limb bones and/or spine/neurovascular injuries
- •Injuries to other knee ligaments
- •Significant knee joint arthritis
- •Local skin infections
结局指标
主要结局
Anterior Drawer's test
时间窗: 12 weeks
Number of patients having grade-1 on the Anterior Drawer's test
Lachman's test
时间窗: 12 weeks
Number of patients having grade-1 on the Lysholm knee score
Lysholm knee score
时间窗: 12 weeks
A higher Lysholm knee score was labeled as effectiveness of the treatment.
次要结局
未报告次要终点
研究者
Muhammad Aamir Latif
Research Consultant
RESnTEC, Institute of Research
