跳至主要内容
临床试验/NCT07269522
NCT07269522已完成不适用

Functional Outcomes of Arthroscopic Anterior Cruciate Ligament Reconstruction by Hamstring Graft With and Without Platelet-Rich Plasma

Muhammad Aamir Latif1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2022年1月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60
试验地点
1
主要终点
Anterior Drawer's test

研究概览

简要总结

No local data exists regarding the outcomes of anterior cruciate ligament reconstruction by hamstring graft with and without platelet-rich plasma. This study aimed to compare the functional outcomes of arthroscopic anterior cruciate ligament reconstruction by hamstring graft with and without platelet-rich plasma.

详细描述

In animal studies, platelet-rich plasma has shown excellent results in accelerating the healing of the anterior cruciate ligament, but studies on human have shown varying clinical outcomes when investigating platelet-rich plasma for its effects on anterior cruciate ligament reconstruction. The findings of this study could provide important insights about the possible role of platelet-rich plasma in arthroscopic anterior cruciate ligament reconstruction by hamstring graft. to enhance early graft healing and reduce early complications, though its long-term effectiveness remains inconsistent. Studies suggest PRP may improve short-to-medium term outcomes like reduced pain and enhanced knee function,

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Any gender
  • Aged 18-40 years
  • With clinically and radiologically confirmed arthroscopic evidence of ACL injury

排除标准

  • With comprised bilateral ACL tears
  • Lack of fitness due to associated comorbidity
  • Fractures of lower limb bones and/or spine/neurovascular injuries
  • Injuries to other knee ligaments
  • Significant knee joint arthritis
  • Local skin infections

结局指标

主要结局

Anterior Drawer's test

时间窗: 12 weeks

Number of patients having grade-1 on the Anterior Drawer's test

Lachman's test

时间窗: 12 weeks

Number of patients having grade-1 on the Lysholm knee score

Lysholm knee score

时间窗: 12 weeks

A higher Lysholm knee score was labeled as effectiveness of the treatment.

次要结局

未报告次要终点

研究者

发起方
Muhammad Aamir Latif
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Muhammad Aamir Latif

Research Consultant

RESnTEC, Institute of Research

研究点 (1)

Loading locations...

相似试验