Framing Messages for Smoking Cessation With Buproprion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 252
- 试验地点
- 1
- 主要终点
- Continuous Smoking Abstinence at 6 weeks
研究概览
简要总结
This is a randomized study of message framing in individuals beginning a smoking cessation program utilizing bupropion SR and brief counseling, videos, and pamphlets.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Pregnant or nursing women, or women of child-bearing potential who are not using an adequate method of contraception
- •Psychiatric illnesses requiring psychotropic medications (i.e., psychosis, major depression, mania), or the presence of suicidality or homocidality
- •Current use of nicotine replacement therapies (i.e., nicotine patch, gum, or lozenges, nasal spray, or inhaler), bupropion (Zyban, Wellbutrin), or marijuana or current participation in another smoking cessation treatment
- •Presence of unstable medical conditions (i.e., cardiac, hepatic, renal disease, diabetes mellitus) that would make a trial of bupropion SR hazardous
- •Have taken monoamine oxidase inhibitors or metoprolol succinate within the past six weeks
- •History of anorexia nervosa or bulimia
- •Previous hypersensitivity to bupropion
- •History of alcohol or other drug dependence in the past one year
- •History of seizure disorder of any etiology (i.e., brain tumor, traumatic brain injury, substance-induced seizures, etc.)
- •Any finding that in the view of the principal investigator would compromise the subject's ability to fulfill the protocol visit schedule and visit requirements or put the subject at risk
- •Sharing home or work environment with current or past participant
- •No couples or participants who see each other every day
研究组 & 干预措施
Gain Framed Absitnence Program
Gain framed video and printed messages encouraging smoking abstinence with Bupropion.
干预措施: Bupropion (Drug)
Gain Framed Absitnence Program
Gain framed video and printed messages encouraging smoking abstinence with Bupropion.
干预措施: Smoking Abstinence Program (Behavioral)
Loss Framed Abstinence Program
Loss framed video and printed messages encouraging smoking abstinence with Bupropion.
干预措施: Bupropion (Drug)
Loss Framed Abstinence Program
Loss framed video and printed messages encouraging smoking abstinence with Bupropion.
干预措施: Smoking Abstinence Program (Behavioral)
结局指标
主要结局
Continuous Smoking Abstinence at 6 weeks
时间窗: 6 weeks
6-week continuous abstinence.
Smoking Cessation at 7 days
时间窗: 7-day point prevalence abstinence
次要结局
未报告次要终点
研究者
Stephanie O'Malley
Director, Division of Substance Abuse Research in Psychiatry
Yale University