Coronary angiography after cardiac arrest
- Conditions
- ACSCardiac arrestcoronary angiography
- Registration Number
- NL-OMON23168
- Lead Sponsor
- fund=intiator=sponsor
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 552
Age > 18
-Comatose patients (Glasgow coma score < 8) with ROSC after OHCA
-Ventricular tachycardia or ventricular fibrillation as initial arrest rhythm. Including patients treated with an AED.
-Signs of STEMI on the ECG at the emergency department (including new LBTB or isolated ST depression in V1-V3 due to an true posterior infarct).
-Hemodynamic instability unresponsive to medical therapy. Defined as a prolonged (>30 min) systolic blood pressure < 100 mm Hg at the time of screening.
-An obvious or suspected non cardiac aetiology of the cardiac arrest.
-A known severe renal dysfunction. (GRF< 30 ml/min)
-Obvious or suspected pregnancy
-Suspected or confirmed acute intracranial bleeding
-Suspected or confirmed acute stroke
-Known limitations in therapy or DO Not Resuscitate-order.
-Known pre-arrest Cerebral Performance Category 3 or 4
->4 hours (240 min from ROSC to screening
-Refractory ventricular arrhythmia
-Known inability to complete 90 day follow up
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Can an immediate CAG and subsequent PCI in patients after OHCA without STEMI improve 90-days survival compared to a delayed CAG and subsequent PCI (after neurological recovery).
- Secondary Outcome Measures
Name Time Method