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Single site randomised trial of fibrin tissue glue versus surgery in the treatment of pilonidal sinus - Fibrin glue versus surgery for pilonidal sinus

Phase 1
Conditions
Pilonidal sinus
Registration Number
EUCTR2004-002065-20-GB
Lead Sponsor
Derbyshire NHS Trust
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

- male and female subjects with pilonidal sinus
- >18 years and <45 years
- only women taking adequate contraceptive precautions
- patientswith no history of allergy to any of the product contents of TISSEEL Kit saealant
- ability to provide valid informed consent
- patients who ahve no objection on moral/religious grounds of the product
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- women who are lactating
- women who are pregnant
- women of childbearing age who are unwilling to take adequate contraceptive
- patients with insufficient command of English to understand patient information or give informed consent

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main Objective: To compare the effectiveness of fbrin tissue glue with standard surgical techniques in the treatment of pilonidal sinus;Secondary Objective: ;<br> Primary end point(s): - reduction in pain<br> - healing rate<br> - return to normal activities<br> - recurrence of pilonidal diease<br> - complications of glue compared to surgery<br>
Secondary Outcome Measures
NameTimeMethod
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