Based on cerebrovascular reactivity, to explore the mechanism of zhu's scalp needle for the treatment of motor function injury in patients with acute ischemic stroke

Phase 1

• Conditions: acute ischemic stroke

• Registration Number: ITMCTR2200006594
• Lead Sponsor: Beijing Fengtai Hospital of Integrated Traditional Chinese and Western Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

(1) Consistent with the diagnosis of acute ischemic stroke in Western medicine;
(2) Patients within 1 week of onset;
(3) persons aged 35-75;
(4) FuGL-Meyer scale score =99;
(5) Patients with first stroke or recurrent stroke had completely returned to normal before the onset of the disease, that is, mRS score =1;
(6) Informed consent has been signed by the patient himself or his legal representative before the clinical study begins;

Exclusion Criteria

(1) Intracranial hemorrhage diseases observed by head CT: patients with cerebral hemorrhage and subarachnoid hemorrhage;
(2) Severe disturbance of consciousness: patients with NIHSS item score of 1a consciousness level > 1;
(3) Transient cerebral ischemia;
(4) Patients with cerebral hernia after admission;
(5) Aphasia patients with stroke;
(6) Patients with cognitive impairment: MMSE score: illiteracy =17, primary school =20, middle school and above =24;
(7) patients with severe hypertension (systolic blood pressure =200mmHg, diastolic blood pressure =110mmHg), diabetes (fasting blood glucose =10mmol/L after hypoglycemic drug treatment) and other diseases, which are still not controlled after treatment;
(8) patients with claudication, osteoarthritis, rheumatoid arthritis, gout arthritis and other diseases affecting limb activities;
(9) Lack of clear imaging diagnostic evidence such as CT and MRI, or imaging diagnostic evidence is insufficient to confirm the diagnosis;
(10) Excluding patients with brain lesions caused by brain trauma, poisoning, post-epileptic state, tumor stroke, encephalitis and serious dysfunction of vital organs;
(11) those who do not cooperate with treatment;

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vm;

Secondary Outcome Measures

Name	Time	Method
Cranial nerve function score;