A Brief Intervention for Cannabis Use
- Conditions
- Cannabis Use Disorder
- Interventions
- Behavioral: Values in Action (VIA)Behavioral: Health Education (HealthEdu)
- Registration Number
- NCT06395389
- Lead Sponsor
- Medical University of South Carolina
- Brief Summary
The purpose of this study is to compare two brief interventions targeting potentially problematic cannabis use in emerging adults (ages 18-25). Brief interventions are two 40-50 minute sessions separated by 1 week. Eligible emerging adults will complete a detailed cannabis assessment (biological and self-report), followed by one of the two brief interventions, and three follow-up assessments: one immediately after the second session and at 1- and 3-months post-intervention. Assignment to the brief intervention is random. Salivary samples will be collected at baseline, post-intervention, and both follow-ups, for a total of 4 samples, to be tested for tetrahydrocannabinol (THC) and cannabidiol (CBD).
- Detailed Description
Cannabis is the most widely used federally illicit substance among emerging adults (age 18-25) in the U.S., and frequent cannabis use is associated with myriad long-term health, social, and academic/occupational consequences. Despite this, rates of perceived risk of daily/regular cannabis use have steadily declined over the past two decades, and this is associated with increased frequency of use, a risk for for Cannabis Use Disorder (CUD). Brief interventions (BIs) are among the most frequently used approaches for addressing problematic or potentially problematic substance use in non-treatment-seeking adolescents and young adults. Although several cannabis brief interventions have been developed and tested to date, meta-analyses indicate that the efficacy of these interventions for emerging adults is mixed and the quality of studies is low, suggesting that novel approaches and rigorous methodology are necessary to improve efficacy. The current study will evaluate the feasibility, acceptability, and preliminary efficacy of a novel cannabis BI for emerging adults who frequently use cannabis.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 62
- Ages 18-25
- Self-Report report cannabis use on at least 20 days of the past 30 days.
- Completion of an Intake Visit (PRO #94743)
- Submit a positive urine cannabinoid test during the Intake Visit
- Currently engaged in substance use treatment for any type of substance use or currently treatment seeking
- History of substance use treatment for any type of substance
- Severe alcohol use disorder or presence of any substance use disorder (SUD) requiring a higher level of care
- Significant or acutely unstable medical or psychiatric problems (i.e., psychosis, mania) that would contraindicate research procedures, interfere with safety, compromise data integrity, or preclude consistent study participation
- Significant risk of suicide or homicide
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Values in Action (VIA) Values in Action (VIA) Brief intervention providing personalized discussion of values/goals, reasons for cannabis use, and strategies to help live in line with values and achieve goals. Health Education (HealthEdu) Health Education (HealthEdu) Brief intervention providing recommendations/advice for good sleep hygiene, nutrition and physical activity, stress, and relationships.
- Primary Outcome Measures
Name Time Method Timeline Followback (TLFB) Baseline, 1-month follow-up, 3-month follow-up, 6-month follow-up The TLFB is a calendar based assessment that is able to capture the frequency and quantity of substance use and other measurable behaviors. Responders identify anchor dates to facilitate recall of days in which substances were used.
- Secondary Outcome Measures
Name Time Method Marijuana Assessment of Problems Inventory (MAPI) Baseline, 1-month follow-up, 3-month follow-up, 6-month follow-up This is a 23-item assessment of the frequency in which problems or negative consequences associated with cannabis use have occurred. For each item, participants select 0 times, 1-2 times, 3-5 times, 6-10 times, or 10+ times in the past month. Higher scores on this inventory indicate a higher frequency of problems or consequences experienced.
Oral Fluid Biospecimen Assay Baseline, 2-week follow-up, 1-month follow-up, 3-month follow-up, 6-month follow-up This is a relatively brief objective assessment of recent cannabis use that is collected through mouth swab and is tested at Forensic Fluids Laboratory for the presence of delta-9 tetrahydrocannabinol (THC), delta-8 THC, and cannabidiol (CBD) using a cut-off of 1 nanogram/liter.
Mini International Neuropsychiatric Interview (MINI) Cannabis Use Disorder Module Baseline, 1-month follow-up, 3-month follow-up, 6-month follow-up This is a 12-item semi-structured clinician interview that assesses diagnostic symptom criteria of cannabis use disorder (CUD) from the Diagnostic and Statistical Manual 5th Edition (DSM-5). Clinicians select either 'yes' or 'no' for the presence of the symptom.
Trial Locations
- Locations (1)
Medical University of South Carolina
🇺🇸Charleston, South Carolina, United States