NCT00121069已完成2 期
Placebo-Controlled Pilot Study of Escitalopram in the Treatment of Specific Phobia
Connor, Kathryn M., M.D.2 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2002年9月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Response based on a criterion of 50% or greater reduction in the Marks Main Phobia Questionnaire and Marks Fear Questionnaire from baseline
研究概览
简要总结
This pilot study is designed to assess the efficacy of escitalopram in the treatment of specific phobia in adult outpatients.
详细描述
This double-blind placebo-controlled pilot trial study is designed to assess the efficacy of 12 weeks of escitalopram vs. placebo in the treatment of specific phobia in adult outpatients. It is hypothesized that escitalopram is safe and effective in the treatment of specific phobia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults 18-65 years of age
- •DSM-IV criteria for specific phobia according to the MINI
- •For women of childbearing potential, a negative serum pregnancy test at screening
- •Written informed consent
排除标准
- •Any current primary DSM-IV diagnosis other than specific phobia
- •History of DSM-IV substance abuse or dependence within the last months
- •Lifetime history of bipolar I disorder, schizophrenia or other psychotic disorder, mental retardation, or other pervasive developmental disorder or cognitive disorder due to a general medical condition
- •Suicide risk or serious suicide attempt within the last year
- •Clinically significant laboratory or EKG abnormality or unstable medical condition
- •For women of childbearing potential, unwillingness to use an acceptable form of contraception during the study
- •Subjects needing concurrent use of psychotropic medications
结局指标
主要结局
Response based on a criterion of 50% or greater reduction in the Marks Main Phobia Questionnaire and Marks Fear Questionnaire from baseline
次要结局
- Response based on CGI-I category
研究者
研究点 (2)
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