The Correlations Between Fluctuations in Anxiety Symptoms and Heart Rate Variability in Patients With Panic Disorder Combined With Agoraphobia: Application of Time Series Analysis in Individual Treatment

Withdrawn

Conditions: agoraphobia
fear of open spaces
10002861

Registration Number: NL-OMON37166

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Withdrawn

Sex: Not specified

Target Recruitment: 3

Inclusion Criteria

- Diagnosed with a panic disorder combined with agoraphobia as described in DSM-IV.
- Women between 18 and 50 years.
- Patients must be willing and capable to keep a diary and wear an accelerometer during their treatment.
- Patients must be willing and capable to wear an ECG device 24 hours a day for two separate weeks

Exclusion Criteria

- Somatic and/or neurological disorders that restrict physical activity
- Patiënts that are diagnosed with psychiatric comorbidity
- Pregnancy
- Pacemaker, medication that influence the ECG

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>With regular time intervals, patients will be asked to fill out a ranking scale<br /><br>on the following subjects in their diary;<br /><br>- Anxiety<br /><br>- Self-esteem<br /><br>- The frequency of panic attacks and exposure (will only be asked at the end of<br /><br>the day)<br /><br>- With whom the patients were<br /><br>- Where they were<br /><br>- Stressful events (if applicable)<br /><br>The physical activity and heart activity will be recorded by an accelerometer<br /><br>and an ambulatory ECG device. The ECG device should be carried 24h a day for<br /><br>two week in total: one week before and one week after the treatment.</p><br>

Secondary Outcome Measures