EFFICACY OF DAPGLIFLOZIN IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION - A RANDOMIZED CONTROLLED TRIAL STUDY
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- IMPROVEMENT OF EJECTION FRACTION OF PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION PATIENT INITIATED ON TABLET DAPAGLIFLOZIN 10MG ONCE A DAY AND REVIEWED AFTER THREE MONTHS OF INITIATION OF THERAPY AND CLINICAL IMPROVEMENT IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION
研究概览
简要总结
THIS STUDY WAS CONDUCTED IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION WHICH WAS IDENTIFIED ACCORDING TO THE INCLUSION AND EXCLUSION CRITERIAS. PATIENTS WERE INITIATED ON SODIUM GLUCOSE CO TRANSPORTER II - TABLET DAPAGLIFLOZIN 10MG ONCE A DAY ON INITIAL VISIT O AND FOLLOWED UP WITH PATIENT ON TABLET DAPAGLIFLOZIN 10MG FOR A PERIOD OF THREE MONTHS AND FOLLOWED UP AT THREE MONTHS FOR REPEAT 2 DIMENSIONAL ECHOCARDIOGRAPHY AND N TERMINAL BRAIN NATREURETIC PEPTIDE WITH ASSESMENT OF CLINICAL IMPROVEMENT OF THE PATIENT ON FOLLOW UP TO DETERMINE THE EFFICACY OF DAPAGLIFLOZIN OF PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •MALE AND FEMALE CONSENTING TO PARTICIPATE IN THE STUDY LEFT VENTICULAR EJECTION FRACTION MORE THAN 50 % PATIENTS WITH INCRASED N TERMINAL PRO BRAIN NATRIURETIC PEPTIDE MORE THAN 300 PG KNOWN TYPE II DIABETES MILLETUS PATIENT NOT ON SODIUM GLUCOSE CO TRANSPORTER II THERAPY.
排除标准
- •PATIENT NOT CONSENTING TO PARTICIPATE IN STUDY CHRONIC KIDNEY DISEASE WITH ESTIMATED GLOMERULAR FILTRATION RATE OF LESS THAN 20 ML PER MINUTE CHRONIC OBSTRUCTIVE PULMONARY DISEASE CHRONIC LUNG DISEASE PATIENTS WITH MYOCARDIAL INFARCTION CORONARY ARTERY BY PASS GRAFT CARDIOMYOPATHIES VALVULAR HEART DISEASE CURRENT OR PRIOR USE OF SODIUM GLUCOSE CO TRANSPORETER II INHIBITORS.
结局指标
主要结局
IMPROVEMENT OF EJECTION FRACTION OF PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION PATIENT INITIATED ON TABLET DAPAGLIFLOZIN 10MG ONCE A DAY AND REVIEWED AFTER THREE MONTHS OF INITIATION OF THERAPY AND CLINICAL IMPROVEMENT IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION
时间窗: Follow up of patients with heart failure with preserved ejection fraction with echocardiography on initial zero visit and follow up at Three months and n terminal pro brain natriuretic peptide at initial visit at o day and followed up for improvement at second visit at three months
次要结局
- CLINICAL IMPROVEMENT IN KCCQ SCORE(2 WEEKS)