Influence of over-the-wire micro-catheters on coronary haemodynamics and the accuracy of physiological indices for assessing the functional significance of intermediate coronary stenoses. - IMPACT

Academisch Medisch Centrum0 个研究点目标入组 32 人开始时间: 待定最近更新: 2024年4月23日

适应症

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•Age > 18 years.;Presence of at least one epicardial stenosis in a native coronary artery, requiring physiological assessment according to the European Society of Cardiology Myocardial Revascularization Guidelines.;Vessel size at least 2.5mm in diameter as visually assessed on the diagnostic angiogram.;Presence of stable; Canadian Cardiovascular Society (CCS) score I-III.;Willing to participate and able to understand, read and sign the informed consent document before the scheduled procedure.

•Left main involvement requiring revascularization.;Cardiac arrhytmia.;Extremely tortuous or calcified coronary arteries that impede adequate physiologic measurements.;Recent (<6 weeks) myocardial infarction (STEMI or NSTEMI).;Severe valvular abnormalities that require surgery. ;Severely impaired left ventricular (LV) function (LV ejection fraction < 30%);LV hypertrophy (>13mm septal wall thickness). ;Unable to undergo percutaneous intervention or receive adenosine (severe reactive airway disease, severe hypotension or high-grade Atrio-Ventricular (AV) block in the absence of a pacemaker. ;Collateral formation in target vessel.;CABG to target vessel.;Tandem stenoses.;Ostial lesions.;Renal failure (MDRD calculated eGFR of <30). ;Pregnancy or planned pregnancy within 12 months after the procedure.

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