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Clinical Trials/NCT02799277
NCT02799277CompletedPhase 4

A Multinomial Process Model of Moral Judgment

University of Texas at Austin1 site in 1 country220 target enrollmentStarted: August 30, 2017Last updated:
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Conditions
Interventions
Drugs

Trial Snapshot

Phase
Phase 4
Status
Completed
Enrollment
220
Locations
1
Primary Endpoint
Moral Dilemma Judgments
Study OverviewStudy DesignEligibility CriteriaArms & InterventionsOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The main goal of this project to investigate the psychological processes underlying moral judgments in social dilemmas. We will examine neuroendocrine determinants of moral judgment by investigating the effects of exogenous testosterone

Detailed Description

  • Medical Screening Interview: Participants will be asked to answer several questions to identify potential medical and non-medical conditions that would preclude the self-administration of testosterone.
  • First Saliva Sample: Participants will be asked provide a saliva sample after they completed the medical screening interview.
  • Testosterone Self-Administration: Immediately following the first saliva collection, participants will self-administer spray puffs of either testosterone or placebo.
  • Relaxation: Participants will be given the opportunity to relax for 30 minutes.
  • Moral Dilemmas Judgments: Participants will be asked to read a set of 24 moral dilemmas that describe situations in which an actor has to make a decision on whether or not to engage in a particular action (e.g., sacrifice the well-being of one person to protect the well-being of several others). Participants will be asked to indicate whether they consider the described action acceptable or unacceptable.
  • Demographics: Participants will be asked to indicate their gender, age, and ethnicity.
  • Ear Temperature, heart rate, and blood pressure will be measured before drug administration, and again 20 minutes after drug administration. If temperature changes more than 2 degrees, heart rate changes more than 20bmp, or if blood pressure changes more than 20%, the experiment will be terminated and subjects will be escorted across the street to the University Emergency Room.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Basic Science
Masking
Triple (Participant, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •must be currently enrolled at The University of Texas at Austin

Exclusion Criteria

  • •not comfortable with the self-administration of testosterone for the purpose of our study less than 18 years old BMI less than 18 or above 27 suffer from any of the physical health conditions listed on the pre-screen questionnaire (I will not ask about mental health because our study is not about mental health) take any of the medications listed on the pre-screen questionnaire currently pregnant (females) irregular cycle in the past 6 months (females) smoke more than 5 cigarettes/day use cocaine more than once/month (**or should I exclude all those who use any drugs recreationally more than once/month?**) drink more than 10 alcoholic beverages/week

Arms & Interventions

Placebo

Placebo Comparator

1ml blank (containing no drug) aqueous solution will be administered intranasally

Intervention: Placebo (Drug)

Testosterone

Experimental

14mg testosterone will be administered intranasally in a 1milliliter aqueous solution

Intervention: Testosterone (Drug)

Outcomes

Primary Outcomes

Moral Dilemma Judgments

Time Frame: 90 minutes

Subjects will decide on whether or not to engage in a particular action (e.g., sacrifice the well-being of one person to protect the well-being of several others). Participants will be asked to indicate whether they consider the described action acceptable or unacceptable.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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