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临床试验/NCT03698643
NCT03698643已完成不适用

Impact of New Interventional Imaging Modality Use (Angio-CT) on Patient Radiation Exposure in Transarterial Chemoembolization

University Hospital, Montpellier1 个研究点 分布在 1 个国家目标入组 145 人开始时间: 2018年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
145
试验地点
1
主要终点
Patient effective radiation dose per TACE

研究概览

简要总结

Transarterial chemoembolization (TACE) is the most performed endovascular interventional radiology (IR) procedure. TACE procedures are performed in an IR suite, most of which are equipped with floor-based flat-panel robotic C-arm allowing two-dimensional imaging. Cone-beam computed tomography (CBCT) has been developed to allow three-dimensional navigation but has several limitations such as reduced signal to noise ratio and small field-of-view, and seems to have negative impact on patient radiation exposure. Another option to perform 3D imaging is called angio-CT which combines a CT-scan and a floor-based flat-panel robotic C-arm in a single IR suite. Even if some publications have shown benefit of angio-CT in TACE procedures in Japan, no study about angio-CT in liver IR procedures has been conducted in the occidental world so far. The purpose of our study was to assess the impact of angio-CT use on patient radiation exposure and treatment quality in TACE procedures compared to CBCT.

This before-after study consisted of a review of consecutive TACE procedures performed between January 2016 and September 2017 in our institution with two different imaging modalities, defining two study groups (C-arm with CBCT versus angio-CT).

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Patient effective radiation dose per TACE

时间窗: 1 day

Patient effective radiation dose (mSv) per TACE : Dose-area product (in mGy/cm\^2) and dose-length product (in mGy/cm) will be combined and converted to report effective dose (in mSv).

次要结局

  • Number of CBCT acquisitions per TACE(1 day)
  • Number of CT acquisitions per TACE(1 day)
  • Tumor response(1 day)
  • Treatment targeting(1 day)
  • Air kerma per TACE(1 day)
  • Fluoroscopy time per TACE(1 day)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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