Non-invasive Substrate Evaluation in Atrial Fibrillation
- Conditions
- C14.280.067.198
- Registration Number
- NCT04496336
- Lead Sponsor
- Hospital Clinic of Barcelona
- Brief Summary
The study aims to assess the right and left atrial electrophysiological substrate in atrial fibrillation patients using the invasive electroanatomic map (basal and with extraestimulus) as well as its correlation with cardiac magnetic resonance and electrocardiographic imaging. The results will also be compared when the patient is in sinus rhythm and atrial fibrillation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 52
- Atrial fibrillation paroxysmal or persistent with criteria for percutaneous ablation
- Cardiomiopathy (FEVI<40%) or significant valvulopathy.
- MRI not possible or contraindicated.
- Previous atrial fibrillation ablation.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation between conduction velocity and MRI fibrosis. Baseline The conduction velocity in sinusal rhythm and with extra estimuli will be correlated with the MRI late gadolinium enhancement sequence (MRI-LGE).
- Secondary Outcome Measures
Name Time Method Correlation between voltage and MRI fibrosis. Baseline The voltage in sinus rhythm and in atrial fibrillation will be correlated with the MRI-LGE.
Correlation between electrocardiographic image (ECGi) and MRI-LGE. Baseline The xxx of the ECGi will be correlated with the MRI-LGE.
Trial Locations
- Locations (2)
Hospital Clinic de Barcelona
🇪🇸Barcelona, Spain
Hospital Gregorio Marañon
🇪🇸Madrid, Barcelona, Spain