imiting weight gain in overweight and obese women during pregnancy to improve health outcomes: a randomised trial.

Not Applicable

Completed

• Conditions: Overweight or obese pregnant women.; Diet and Nutrition - Obesity; Reproductive Health and Childbirth - Other reproductive health and childbirth disorders

• Registration Number: ACTRN12607000161426
• Lead Sponsor: Women's and Children's Hospital, Adelaide, SA.

Brief Summary

We conducted a study to determine whether a dietary and lifestyle intervention during pregnancy for women who were overweight or obese would improve pregnancy and birth outcomes. Overweight and obesity in pregnancy increases risks of some adverse outcomes for women and their babies. These risks include caesarean birth, gestational diabetes, high infant birth weight which in turn increases the risk of childhood obesity. This multicentre randomised trial was conducted in three public maternity hospitals across South Australia. The participants were women with a singleton pregnancy, between 10+0 and 20+0 weeks’ of pregnancy, and had a BMI of 25 kg/m2 or more. 2212 women were enrolled, 1108 of the women were randomised to a comprehensive dietary and lifestyle intervention delivered by research staff; 1104 were randomised to standard care and received pregnancy care according to local guidelines, which did not include such information. For women who were overweight or obese, the antenatal lifestyle advice used in this study did not reduce the risk delivering a baby being born with birthweight larger than expected for the number of weeks of pregnancy when it was born and the baby’s sex. Although the women in the dietary and lifestyle intervention group improved the quality of their diet and increased their physical activity, they gained a similar amount of weight during pregnancy as women in the control arm of the study. Women in the intervention arm of the study were less likely

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-03-09
• Study Completion: 2012-12-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 2212

Inclusion Criteria

Pregnant women with a singleton, live gestation between 10+0 - 20 weeks who are obese or overweight (defined as a body mass index greater that 25kg/m2).

Exclusion Criteria

Women with multiple pregnancy, or type 1 or type 2 diabetes diagnosed prior to pregnancy.There is no age range criteria for this trial.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Infant large for gestational age at birth (defined as birth weight = 90th centile for gestational age).[At birth]