Investigating health effects of fibre consumption in healthy humans

Not Applicable

Completed

• Conditions: Gut disease; Asthma; Inflammatory Bowel Disease; Allergies; Diet and Nutrition - Other diet and nutrition disorders; Inflammatory and Immune System - Normal development and function of the immune system; Metabolic and Endocrine - Normal metabolism and endocrine development and function; Oral and Gastrointestinal - Inflammatory bowel disease

• Registration Number: ACTRN12619000845134
• Lead Sponsor: Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-09-10
• Study Start: 2019-06-14
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Healthy adults

Exclusion Criteria

Inflammatory conditions (i.e asthma, inflammatory bowel disease, rheumatoid arthritis, allergy)
Recent bacterial or viral infection (<4 weeks)
Current or recent (<4 weeks) use of probiotics, antibiotics or medications that potentially alter normal gut function
Pregnancy or current breastfeeding
Special dietary requirements (i.e. allergy, vegetarian, vegan)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood Short-chain fatty acid level[Morning of Day 5 of intervention and control diet]

Secondary Outcome Measures

Name	Time	Method
Proportion of peripheral blood T-regulatory cells[Morning of Day 5 of intervention and control diet];This is a composite secondary outcome measuring Blood cytokine levels.<br>Interleukin (IL)-10, IL-17A, IL-1B, IL-6, IL-8 and Tumour necrosis factor (TNF)-a<br>Measured by multiplex analysis [Morning of day 5 of intervention and control diet]