mbilical cord serum therapy in acute ocular chemical burns

Completed

• Conditions: Acute chemical ocular burns; Injury, Occupational Diseases, Poisoning; Burn and corrosion confined to eye and adnexa

• Registration Number: ISRCTN08131903
• Lead Sponsor: Dr Rajendra Prasad Centre for Ophthalmic Sciences (India)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07-05
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

1. Patients with acute ocular chemical burns (grade III, IV and V according to Dua classification) presenting within three weeks of injury
2. Either sex, aged 16 - 50 years

Exclusion Criteria

1. Patients with grade I, II and VI injury
2. Impending perforation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patients were followed up on day 1, day 3, day 7, day 14, day 21 and at the end of 1 month, 2 months and 3 months. Total duration of follow up in all three groups was 3 months.<br>Parameters assessed were at each follow-up included:<br>1. Pain score<br>2. Best corrected visual acuity<br>3. Limbal ischaemia<br>4. Epithelial defect<br>5. Corneal clarity and vascularisation<br>6. Tear film status (Schirmer, TBUT)<br>7. Intraocular pressure (IOP)<br>8. Symblepharon formation

Secondary Outcome Measures

Name	Time	Method
Complications arising from injury and/or treatment