Stellate Ganglion Block as Novel Treatment for Heart Failure Patients
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 108
- 试验地点
- 2
- 主要终点
- Change of left ventricular ejection fraction (LVEF).
研究概览
简要总结
Stellate Ganglion Block as Novel Treatment for Heart Failure Patients
详细描述
Stellate Ganglion Block as Novel Treatment for Heart Failure Patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 : 70 years old.
- •NYHA Class III-IV Heart Failure.
- •Heart failure with a reduced ejection fraction (HFrEF) LVEF ≤ 40% calculated using 2D echocardiography and Biplane Simpson's .
- •Optimal tolerated Medical Therapy for Heart Failure.
排除标准
- •Active Malignancy.
- •Acute heart failure including pulmonary edema or cardiogenic shock.
- •Severe, life-threatening non-cardiac disease.
- •Pregnancy.
- •Localized infection.
- •Coagulopathy or anticoagulated patients.
- •Refused this procedure.
研究组 & 干预措施
Narrow QRS complex Heart failure patients
Narrow QRS complex Heart failure patients with optimal medical treatment.
: Narrow QRS complex Heart failure patients
: Narrow QRS complex Heart failure patients with optimal medical treatment with stellate ganglion block.
干预措施: Stellate Ganglion Block (Procedure)
Wide QRS complex heart failure patients
Wide QRS complex heart failure patients with optimal medical treatment who were non responders to CRT( retrospective and prospective) with stellate ganglion block.
干预措施: Stellate Ganglion Block (Procedure)
结局指标
主要结局
Change of left ventricular ejection fraction (LVEF).
时间窗: 3 month
Change of left ventricular ejection fraction (LVEF).
Change of NYHA classification.
时间窗: 3 month
Change of NYHA classification.
次要结局
- Vascular complications and safety issues.(3 month)
- Cardiovascular death.(3 month)
- Change of 6 minutes walking test.(3 month)
- Heart failure hospitalization.(3 month)
研究者
Mina sobhi said fam
resident doctor
Assiut University