The Influence of Hip Replacement on Lower Extremity Hemodynamics in Crowe IV Hip Dysplasia Patient
- Conditions
- Hip Dysplasia
- Registration Number
- NCT04157842
- Lead Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Brief Summary
Explore the influence of hip replacement on lower extremity hemodynamics in Crowe Ⅳ hip dysplasia patient.
- Detailed Description
Changes of limb length after total hip replacement is common, especially for Crowe Ⅳ hip dysplasia patient. Such change potentially increases tension of vessel and influence lower extremity hemodynamics. Till now, little is known in this area.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
- Unilateral Crow IV hip dysplasia;
- Bilateral Crow IV hip dysplasia without osteoarthritis on the other side
- Patients with serious medical disease;
- Patients with lower extremity vascular disease; 3. Patients with severe mental illness.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Radiographic Results 1 week, 12 weeks, 24 weeks and 1 year after the surgery. change of Radiographic Results from 1 week after surger to 1 year after surgery
Lower Limb Arterial CT Angiography preoperative, 1 week, 12 weeks after the surgery. change of vascular diameter and vascular cross-sectional from baseline(preoperative) to 1 year after surgery baseline(preoperative) to 12 weeks after surgery.
Blood Viscosity preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery. change of blood viscosity from baseline(preoperative) to 1 year after surgery.
Hip Harris Score preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery. change of hip harris score scale from baseline(preoperative) to 1 year after surgery.
Vascular Ultrasound Examination preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery. change of systolic peak velocity, end-diastolic velocity, pulsation index, resistance index and blood flow from baseline(preoperative) to 1 year after surgery.
Leg Length Change preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery. change of Leg Length from baseline(preoperative) to 1 year after surgery.
- Secondary Outcome Measures
Name Time Method