application of growth factors after deep cleaning in the type 2 diabetes mellitus patient having gum disease.

Completed

Conditions: Chronic periodontitis, (2) ICD-10 Condition: E119||Type 2 diabetes mellitus without complications,

Brief Summary: Subjects with Diabetes mellitus are prone to have more periodontal destruction than when compared to healthy individuals. uncontrolled Diabetes mellitus subjects respond poorly to the nonsurgical periodontal therapy alone in management of periodontal pockets. Hence, in this study we would like be clinically evaluate the adjunctive benefits of injectable platelet rich fibrin (i-PRF) along with scaling and root planing in periodontitis subjects with type 2 Diabetes mellitus(HbA1c>7).

Recruitment & Eligibility

Inclusion Criteria

1.Type 2 Diabetes mellitus subjects with the glycaemic status having HbA1c â‰¥ 7 2.Subjects on oral medication for the management of Diabetes mellitus.
3.Subject with moderate periodontal disease with the case definition, StageIII and Grade C periodontitis, according to EFP-AAP periodontal disease classification 2017.
i.e., Moderate periodontal destruction is defined as sites having â‰¥ 5mm probing pocket depth with attachment loss.
4.Moderate periodontal destruction at least, in 2 interproximal sites in each mandibular quadrant.
5.Minimum presence of 4 permanent teeth per mandibular quadrant (excluding 3rd molars).

Exclusion Criteria

1.Sites with pseudo pockets / advanced periodontal destruction with mobility and Grade IV furcation involvement 2.Periodontal therapy within last 6 months 3.Previous history of intake of antibiotics over last 6 months 4.Systemic condition / disease other than Type II DM, having influence on course and treatment outcomes of periodontal disease.
5.Screening for the infectious disease will be done and the subjects with infectious diseases will be excluded.
6.Individuals with known platelet disorders 7.Smokers.

Primary Outcome Measures

Name	Time	Method
To evaluate the changes in the:	Baseline \| 3Months \| 6Months
Clinical attachment level (CAL)	Baseline \| 3Months \| 6Months
before and after therapy within and between the groups.	Baseline \| 3Months \| 6Months

Secondary Outcome Measures

Name	Time	Method
To evaluate the changes in the	1.Probing pocket depth (PPD)

Locations (1): SRM dental College
🇮🇳
Chennai, TAMIL NADU, India
SRM dental College
🇮🇳Chennai, TAMIL NADU, India
Shunmuga Prasanth
Principal investigator
9003208920
prasanthalur@gmail.com