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Heparin Pharmacokinetics in Response to Temperature Variation during Cardiopulmonary Bypass

Not Applicable
Conditions
Anticoagulant use
Surgery requiring cardiopulmonary bypass
Therapeutic intra-operative hypothermia
Surgery - Other surgery
Blood - Clotting disorders
Cardiovascular - Other cardiovascular diseases
Anaesthesiology - Other anaesthesiology
Registration Number
ACTRN12621001270808
Lead Sponsor
Department of Anaesthesia, Austin Health
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
All
Target Recruitment
40
Inclusion Criteria

Patient undergoing cardiac surgery requiring cardiopulmonary bypass

Exclusion Criteria

Administration of therapeutic low molecular weight heparin or unfractionated heparin infusion < 24 hours prior to planned cardiac surgery
End-stage renal failure or anticipated requirement for haemofiltration on cardiopulmonary bypass
Anticipated duration of cardiopulmonary bypass < 60 minutes
Plan for intra-operative cooling below 25°C
BMI > 30 kg/m²
Patients unable to give informed consent

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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