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Clinical Trials/NCT04864132
NCT04864132
Completed
N/A

The Investigation Of Exercise Capacity And Exercise-Induced Fatigue in Young Adults Who Survived From Coronavirus

Biruni University1 site in 1 country60 target enrollmentMay 27, 2021
ConditionsCovid19

Overview

Phase
N/A
Intervention
Not specified
Conditions
Covid19
Sponsor
Biruni University
Enrollment
60
Locations
1
Primary Endpoint
Submaximal and maximal exercise tests
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The effects of Coronavirus Disease (COVID-19), a multisystem disease, on the body system and functions are being investigated all over the world. Examining the effect of exercise capacity, which is an important marker of cardiovascular risk in young individuals with COVID-19, will allow the planning of exercise and physical activity programs according to the needs of that specific population. The objectives of this project are:(1) To compare the submaximal and maximal exercise capacity of young adults aged between 18-30 who have had COVID-19 with healthy individuals in the same age group (2) To determine the roles of muscle strength, respiratory functions, fatigue, dyspnea, and physical activity level on exercise capacity evaluated by two different tests in young adults survived from COVID-19.

Detailed Description

The effects of COVID-19, a multisystem disease, on the body system and functions are being investigated worldwide. For young adults, exercise capacity is vital in the workforce, cardiovascular risk factors and long-term health perception. Determining exercise capacity, which is an essential indicator of cardiovascular risk in the long term, and determining the factors affecting exercise capacity in cases with COVID-19 will allow the planning of exercise and physical activity programs according to young people's needs. The objectives of this project are:(1) To compare the submaximal and maximal exercise capacity of young adults aged between 18-30 who have had COVID-19 with healthy individuals in the same age group (2) To determine the roles of muscle strength, respiratory functions, fatigue, dyspnea, and physical activity level on exercise capacity evaluated by two different tests in young adults survived from COVID-19. There is no study in the literature evaluating the exercise capacity and the factors affecting the prolonged COVID-19 symptoms for patients with COVID-19. This project can provide objective evidence on this subject and includes controlled multi-directional measurement.

Registry
clinicaltrials.gov
Start Date
May 27, 2021
End Date
November 15, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Biruni University
Responsible Party
Principal Investigator
Principal Investigator

Buket AKINCI

Associated Proffesor

Biruni University

Eligibility Criteria

Inclusion Criteria

  • For cases with COVID-19:
  • Confirmed COVID-19 infection - For healthy individuals of the same age group who have not had COVID-19: Individuals who have not been diagnosed with COVID-19 as of March 11, 2020 and who have not been in contact and risky according to the "Life Fits Into Home" application
  • For all participants; Answering "No" to all questions in the Physical Activity Readiness Questionnaire.

Exclusion Criteria

  • Individuals with orthopedic or neurological disabilities that may interfere with exercise testing,
  • Individuals with a fever\> 38 ° C and / or resting blood pressure \<90/60 mmHg or\> 140/90 mmHg and/or oxygen saturation ≤95%,
  • Individuals who have been involved in a physiotherapy and rehabilitation program within the last 3 months,
  • Individuals with insufficient cooperation
  • Individuals with blood coagulation disorders contraindicated for blood lactate analysis,
  • Pregnant women or individuals with suspected pregnancy

Outcomes

Primary Outcomes

Submaximal and maximal exercise tests

Time Frame: 1 year

The 6 minutes walking distance and incremental shuttle walk distance will be measured.

Secondary Outcomes

  • Peripheral muscle strength(1 year)
  • Forced vital capacity (FVC) (predicted %)(1 year)
  • Fatigue Severity Scale(1 year)
  • Forced expiratory volume in first second (FEV1) (predicted %)(1 year)
  • Respiratory muscle strength(1 year)
  • FEV1/FVC (predicted %)(1 year)
  • International Physical Activity Questionnaire-Short Form (IPAQ)(1 year)
  • Dyspnea-12 Scale(1 year)

Study Sites (1)

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