ACTRN12621000244808进行中（未招募）未知
Effect of periodontitis treatment on histone deacetylase expression levels in patients with periodontal disease: a prospective clinical study
niversity of Queensland0 个研究点目标入组 40 人开始时间: 2021年3月8日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 35 Years 至 o limit（—）
- 性别
- All
入选标准
- •Patients 35 years of age or older.
- •For the periodontal health group:
- •No history of Stage III and IV periodontitis. BOP<10% and PPD<=3mm
- •For the gingivitis group*:
- •>=30% BOP and PPD<=3mm
- •For the periodontitis group*:
- •Generalised Stage III and IV Periodontitis, defined by:
- •>=30% sites with interdental CAL of at least 1-2mm and radiographic bone loss.
- •Interdental CAL >=5mm
- •Radiographic bone loss extending to middle third of root and beyond
- •Tooth loss due to periodontitis
- •Probing depths >=6mm
- •Class II or III furcation involvement
- •*Based on Chapple et al 2018
排除标准
- •Current smokers
- •Uncontrolled diabetes (HbA1c>=6.5)*
- •Long-term use of immunosuppressive or anti-inflammatory drugs, periodontal treatment or antibiotics therapy six months prior to investigation
- •*Based on American Diabetes Association 2018
研究者
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