跳至主要内容
临床试验/CTRI/2024/11/077433
CTRI/2024/11/077433招募中不适用

Investigating the Magnetic Resonance Imaging Cross-section area that best correlates with intraoperative hamstring auto graft size.

Rajendra Institute of Medical Sciences1 个研究点 分布在 1 个国家目标入组 41 人开始时间: 2024年12月1日最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
41
试验地点
1
主要终点
The primary objective of this study is to investigate the feasibility and accuracy of utilizing pre-operative MRI scans to predict the intraoperative hamstring graft size in patients undergoing anterior cruciate ligament (ACL) reconstruction surgery.

研究概览

简要总结

The primary function of the ACL is to prevent anterior translation of the tibia relative to the femur. Other functions of the ACL include resisting internal rotation of the tibia and varus or valgus stress of the tibia in the presence of collateral ligament injury.Rupture of ACL is one of the most common  ligamentous injuries of the knee  with an incidence of 68.6 per 100,000 population. The incidence of reconstruction of the anterior cruciate ligament has been reported as high as 75,000–100,000 per year in the India. It is most commonly caused by sports injuries, however in India, it is mainly caused by road traffic accidents.

Anterior cruciate ligament (ACL) injury is very frequent, not only in professional athletes but also–increasingly often- in people who practice sports regularly. Conservative treatment usually fails to eliminate recurrent symptoms during the return to activities. Additionally, with subsequent instability episodes, patients may show an accelerated onset of degenerative joint changes and meniscal injuries. ACL reconstruction aims to eliminate symptoms and prevent such degenerative joint changes.ACL reconstruction restores the stability of the knee joint and protects the menisci and joint surfaces from further damage,6and prevents worsening of existing chondral lesions as well as occurrence of newer lesions. Reconstruction of the ACL may also alter the incidence of osteoarthritis in the longer term. Also, ACL does not have the potential to adequately heal by itself when torn, therefore surgical ACL reconstruction is generally the treatment of choice. Large variation in tendon size between individuals makes hamstring graft diameter for anterior cruciate ligament (ACL) reconstruction unpredictable. Inadequate graft diameter may necessitate an alternative source of tissue requiring pre-operative planning. The purpose of this study was to determine whether, magnetic resonance image (MRI) measurements and clinical anthropometric data are predictive of hamstring tendon graft diameter.

研究设计

研究类型
Observational

入排标准

年龄范围
20.00 Year(s) 至 45.00 Year(s)(—)
性别
All

入选标准

  • Young Adults (20 – 45 yr).
  • Patients with chronic ACL Injury.
  • Patients with ACL injury associated with Meniscal Injuries.

排除标准

  • Patients with acutely injured Knee.
  • Patients with history of previous Knee surgeries.
  • Patients with infection of the Knee.
  • Patients with degenerative joint disease of the Knee.
  • Patients with stiff Knee with deformity.
  • Patients with associated metabolic disorders.
  • Patients with associated inflammatory disorders.

结局指标

主要结局

The primary objective of this study is to investigate the feasibility and accuracy of utilizing pre-operative MRI scans to predict the intraoperative hamstring graft size in patients undergoing anterior cruciate ligament (ACL) reconstruction surgery.

时间窗: 1 Year

次要结局

  • 1.To determine the extent of correlation between specific pre-operative MRI measurements and the actual intraoperative hamstring graft size.(2.To develop a predictive model based on the pre-operative MRI data that can estimate the intraoperative hamstring graft size with a high level of accuracy.)

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Anil Kumar Das

Rajendra Institute of Medical Sciences

研究点 (1)

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