Helicobacter Pylori Empiric Treatment in Ulcer Bleeding
Phase 4
- Conditions
- Peptic Ulcer Hemorrhage
- Registration Number
- NCT00687336
- Lead Sponsor
- Hospital de Sabadell
- Brief Summary
The goal of the study is to compare the effectiveness of empirical Helicobacter pylori treatment compared with treatment depending on diagnostic tests for Helicobacter pylori in patients with Upper gastrointestinal bleeding due to peptic ulcer. Main hypothesis is that empirical treatment will reduce the number of patients lost to follow-up thus improving the cure rates of Hp infection.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 178
Inclusion Criteria
- Patients older than 18.
- Informed Consent signed.
- Diagnosis of no variceal upper gastrointestinal bleeding secondary to a duodenal ulcer, erosive duodenitis or gastric ulcer.
- Life expectancy longer than 6 months.
- Able to attend further clinical controls.
- Absence of the following exclusion criteria.
Exclusion Criteria
- Previous eradication treatment.
- Use of antibiotics 2 weeks prior to inclusion.
- Need for Antisecretor treatment that cannot be stopped to perform the breath test.
- Pregnancy or breastfeeding.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Helicobacter pylori eradication rate two years
- Secondary Outcome Measures
Name Time Method Economical evaluation through cost-effectivity study of the empiric erradicator Helicobacter pylori treatment. two years
Trial Locations
- Locations (1)
Hospital de Sabadell, Institut Universitari Parc Tauli
🇪🇸Sabadell, Barcelona, Spain
Hospital de Sabadell, Institut Universitari Parc Tauli🇪🇸Sabadell, Barcelona, Spain