Prison-Based HIV Partner Notification

Not Applicable

Not yet recruiting

• Conditions: HIV

• Registration Number: NCT07103928
• Lead Sponsor: University of Illinois at Chicago

Brief Summary

Assisted partner notification (APN) is a voluntary and confidential process that utilizes specially-trained health workers to encourage and assist people diagnosed with HIV to inform their sex and drug use partners about possible shared exposure to HIV. With APN, partners who have come in contact with HIV are notified about exposure and given information to protect themselves from contracting HIV in the future or to begin treatment, if needed.

This study compares two types of HIV partner notification. Incarcerated men with HIV will be recruited as "index participants". Participants in both groups will be encouraged to notify sex and needle-sharing partners with whom they may have shared an HIV exposure before incarceration. All participants have the option to self-notify partners during a prison visitation or telephone call. In addition, participants randomized to an APN Choice group also can opt for anonymous notification by specially-trained APN notifiers that includes contact tracing if needed. As outcomes, we will compare the number of partners in each condition who are notified, HIV tested, diagnosed, and linked to HIV treatment. The study will show if prison-based APN is successful in reaching partners for HIV testing.

Detailed Description

This study will evaluate the effectiveness of Impart, an assisted partner notification (APN) intervention that was developed to increase HIV testing and referral into treatment among the sex and drug use partners of incarcerated people with HIV. Incarcerated people with HIV are assigned randomly to one of two groups. Participants assigned to the Impart Choice condition may choose to inform partners themselves by telephone or in person or they may ask specially-trained nurses and outreach workers to confidentially notify partners and to offer partners HIV testing. Meanwhile, participants assigned to the Standard of Care Self-Tell Notification Only condition will be encouraged to tell their partner(s) themselves, either by phone or in person during a prison visitation. As outcomes, we will compare after six weeks the number of partners in each condition who are notified, HIV tested, diagnosed, and linked to confirmatory HIV testing and treatment After 6 weeks, we will offer outreach-assisted partner notification to any participant who was randomized to or initially chose to notify their partners themselves. Results from the study will provide evidence as to the use of prison-based APN in making partner notification desirable and acceptable to people in prison while also reducing barriers to partner notification and HIV testing for their partners in the community.

Study Timeline

• Status Verified: 2025-07
• Study First Submitted: 2025-07-29
• Study First Submitted QC: 2025-07-29
• Last Update Submitted: 2025-07-29
• Study First Posted: 2025-08-05
• Last Update Posted: 2025-08-05
• Study Start: 2026-01-01
• Primary Completion: 2028-12
• Study Completion: 2028-12-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Male
• Target Recruitment: 216

Inclusion Criteria

• HIV-diagnosed
• Sexually active (penile-vaginal or penile-anal) and/or sharing injection equipment during the year before incarceration

Exclusion Criteria

• Incarcerated more than 5 years

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
HIV Testing	6 weeks after randomization	Number of partners who complete HIV testing

Secondary Outcome Measures

Name	Time	Method
First HIV Test	6 weeks post-randomization	Number of partners who are HIV testing for the first time
HIV Diagnosis	6 weeks post-randomization	Number of partners who are HIV diagnosed
ART Linkage	6 weeks post-randomization	Number of HIV-diagnosed partners who are evaluated for treatment by a physician
HIV Notification	6 weeks post-randomization	Number of partners who are notified of possible shared exposure to HIV
ART Initiation	6 weeks post-randomization	Number of HIV-diagnosed partners who initiate treatment with antiretroviral therapy (ART)

Trial Locations

Locations (1)

Fakultas Ilmu Keperawatan, Universitas Indonesia; 🇮🇩 Depok, Jawa Barat, Indonesia