Primary ventricular fibrillation and sudden death during a first myocardial infarction: Genetic basis
- Conditions
- Myocardial infarctionCirculatory System
- Registration Number
- ISRCTN11980212
- Lead Sponsor
- niversità degli Studi di Pavia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 4000
Cases:
1. Age between 18 and 75 years, inclusive
2. At least one episode of cardiac arrest due to ventricular fibrillation within 24 h of onset of symptoms of heart attack documented in the index electrocardiogram
Controls:
1. Age between 18 and 75 years, inclusive
2. Episode of myocardial infarction within 24 h of onset of symptoms
Case Patients
1. Age younger than 18 or older than 75 years
2. History of previous myocardial infarction
3. Pre-existing significant cardiac disease and / or associated with Ejection Fraction less than or equal to 30%
4. Presence of arrhythmogenic diseases that affect the occurrence of major ventricular arrhythmias (TV, FV) independently by the ischemic event (arrhythmogenic right end/or left ventricular cardiomiopathies, long- and short-QT syndrome; Brugada syndrome and Cathecolaminergic polymorphic ventricular tachicardia)
Control Patients
1. Age younger than 18 or older than 75 years
2. History of previous myocardial infarction
3. Pre-existing significant cardiac disease and / or associated with Ejection Fraction less than or equal to 30%
4. Presence of arrhythmogenic diseases that affect the occurrence of major ventricular arrhythmias (TV, FV) independently by the ischemic event (arrhythmogenic right end/or left ventricular cardiomiopathies, long- and short-QT syndrome; Brugada syndrome and Cathecolaminergic polymorphic ventricular tachicardia)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method