Prospective study of intensity-modulated radiation therapy using standard radiation dose for high-grade glioma
Not Applicable
- Conditions
- High-grade glioma
- Registration Number
- JPRN-UMIN000022502
- Lead Sponsor
- Kagawa University Hospital
- Brief Summary
The completion rate of IMRT was 100%. The median follow-up period was 29 months (range=6-68 months). Median OS and PFS were 30 and 14 months, respectively. No patients experienced Grade 3 or higher non-hematological toxicity. The 2-year OS rates were 100%, 57%, and 33% in Radiation Therapy Oncology Group-Recursive Partitioning Analysis (RTOG-RPA) classes I/II, IV, and V, respectively (p=0.002; log-rank test).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1. No prior radiation therapy for intracranial disease 2. Prior treatment for high-grade glioma 3. Women during pregnancy, possible pregnancy, or breast-feeding, patient who wish pregnancy 4. Psychiatric disease 5. Inappropriate patients for this study judged by physicians
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method