Long-term Paired Associative Stimulation in Rehabilitation of Spinal Cord Injury Patients
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 5
- Locations
- 1
- Primary Endpoint
- Daniels and Worthingham's Muscle Testing
Study Overview
Brief Summary
The investigators have recently shown in two pilot incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles (1). In this study, the investigators will administer long-term paired associative stimulation to incomplete SCI patients in a long-term manner, keeping each patient in the study for as long as continuous improvement is observed.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •incomplete SCI
Exclusion Criteria
- •metal inclusion in the head area
- •pacemaker
- •hearing device
- •high intracranial pressure
Arms & Interventions
incomplete SCI patients
Intervention: long-term paired associative stimulation (Device)
Outcomes
Primary Outcomes
Daniels and Worthingham's Muscle Testing
Time Frame: 1 month after the last stimulation session
Daniels and Worthingham's Muscle Testing
Time Frame: 2 days after the last stimulation session
Secondary Outcomes
No secondary outcomes reported
Investigators
Anastasia Shulga
Principle Investigator
Helsinki University Central Hospital