An eight week pilot study to investigate the effect of oscillation device on breathlessness in patients with chronic obstructive pulmonary disease

Completed

• Conditions: Chronic obstructive pulmonary disease (COPD); Chronic obstructive pulmonary disease; Respiratory

• Registration Number: ISRCTN81979106
• Lead Sponsor: niversity Hospitals of Leicester

Brief Summary

1. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29535259 (added 24/01/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-24
• Study Completion: 2016-12-31
• Last Update Posted: 11 February 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

1. Participant is willing and able to give informed consent for participation in the study
2. Male or Female, aged 40 years or above
3. Confirmed diagnosed of COPD
4. MRC Score of 3 or more. (walk slower than people of the same age on the level or stops for breath when walking at own pace on the level)
5. Able to read and write in English

Exclusion Criteria

1. Significant disease (other than COPD) that could cause dyspnoea or exercise limitation
2. Contraindications for exercise (unstable cardiovascular disease; hypertension etc, a full list is described by the American College of Sports Medicine and is routine deployed)
3. Inability/unwillingness to use the device
4. Contraindications to using HFAO device (including severe right heart failure with hypotension), current severe haemoptysis, ineffective cough, rib fractures, pregnancy, current or recent pneumothorax, epilepsy, current pulmonary embolism, oesophageal varices, recent thoracic, upper gastro-intestinal tract or facial surgery)
5. Previously engaged in exercised based research or pulmonary rehab in the last 6 months.
6. Inability to secure informed consent
7. Those unable to communicate in full English will be excluded as the user manual is only available in English

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Breathlessness at baseline and after 8 week of HFAO, measured using the Chronic respiratory Questionnaire (CRQ) Dyspnoea domain