Evaluation of Gabapentin as a drug that helps in postoperative pain management of Knee Surgery
- Conditions
- Sprain and strain involving (anterior) (posterior) cruciate ligament of kneeM00-M99
- Registration Number
- RBR-3zvc3s
- Lead Sponsor
- Instituto de Ortopedia e Traumatologia de Joinville
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Patients of both genders, aged between 18 and 50 years; with single lesion of the unilateral Anterior Cruciate Ligament; who undergo surgical treatment of a single lesion of the Anterior Cruciate Ligament.
Patients who present allergy to Gabapentin, Tramadol, Dipyrone or Nimesulide (prior or during the study); Renal or Hepatic Insufficiency; patients with recent previous use of anticonvulsants, opioids, or antidepressant agents; or who are being treated with cimetidine or antacids for any reason; associated chondral lesion; injury of another associated ligament; associated meniscal injury; diabetes mellitus; fibromyalgia; chronic pain; depressive disorder, bipolar disorder, generalized anxiety disorder; history of illegal substance use or alcohol abuse; non-literate patients and those who do not agree to sign the Informed Consent Form.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Patients receiving Gabapentin in the Multimodal Analgesia scheme (Gabapentin Group) will consume fewer opioids in the recent postoperative period than patients who received Placebo in the same Multimodal Analgesia scheme (Placebo Group).<br>
- Secondary Outcome Measures
Name Time Method 1. Patients in the Gabapentin Group will present lower scores on the Pain Scales compared to those in the Placebo Group.<br>2. Gabapentin Group patients will have fewer adverse effects than Placebo Group patients.