Assessment of Clinical Effects of Coenzyme Q10 Levels in COVID-19 Patients in Intensive Care Unit

• Conditions: COVID-19
• Interventions: Diagnostic Test: blood sample

• Registration Number: NCT05058716
• Lead Sponsor: Hacettepe University

Brief Summary

The study will be done in Hacettepe University Anesthesiology and Reanimation Intensive Care Unit. The investigators will accept COVID-19 diagnosed or suspected patients to the ICU. In the first day of hospitalization and after that once a week, the investigators will take blood samples from the patients to evaluate Coenzyme q10 levels. Our hypothesis is that there is a relationship between low coenzyme q10 levels and poor clinical outcome.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2021-01-01
• Study First Submitted: 2021-09-22
• Study First Submitted QC: 2021-09-27
• Study First Posted: 2021-09-28
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-15
• Last Update Posted: 2022-03-17
• Primary Completion: 2022-10-01
• Study Completion: 2022-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

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Exclusion Criteria

• being under the age of 18
• being pregnant
• patient refusal

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
COVID-19 negative patients	blood sample	-
COVID-19 positive patients	blood sample	-

Primary Outcome Measures

Name	Time	Method
duration of mechanical ventilation	from the first day of hospitalization and during ICU stay period	days
mortality	from the first day of hospitalization until the date of death from any cause	yes or no
duration of vasopressor agent requirement	from the first day of hospitalization and during ICU stay period	days

Secondary Outcome Measures

Name	Time	Method
any organ failure	from the first day of hospitalization until the date of death from any cause or discharge from ICU	yes or no
new thromboembolic event	from the first day of hospitalization until the date of death from any cause or discharge from ICU	yes or no
hospital stay period	from the first day of discharge from ICU to ward until the date of death or discharge from the hospital	days
ICU stay period	from the first day of hospitalization until the date of death from any cause or discharge from ICU	days

Trial Locations

Locations (1)

Hacettepe University Hospital; 🇹🇷 Ankara, Altındağ, Turkey