Metabole effecten van groeihormoon.
- Conditions
- Growth HormoneGrowth hormone deficiencyDiagnostic problems of growth hormone tests
- Registration Number
- NL-OMON24096
- Lead Sponsor
- Maastricht University Medical Centre (MUMC)PO box 58006202 AZ MaastrichtThe NetherlandsTelephone+31 43 387 5239
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
1. All children scheduled for growth hormone treatment, fulfilling the next criteria:
A. Children born small for gestational age without catch up growth;
Exclusion Criteria
1. Children with a chronological or bone age greater than 8 years for girls and 10 years for boys, because of the influence of puberty;
2. Children younger that 4 years of age;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The relation between short time effects of rhGH treatment on total body water (TBW) and total energy expenditure (TEE) in growth hormone deficient and small for gestational age children and the long-term change in height SDS after one year.
- Secondary Outcome Measures
Name Time Method What effect has GH on a number of metabolic risk parameters that are typical parameters for the metabolic syndrome in adults?