EUCTR2014-001550-42-AT进行中(未招募)1 期
Patient stratification and treatment response prediction in neuropharmacotherapy using PET/MR – Predicting drug efficacy using hybrid PET/MR imaging with pharmacological challenge and multireceptor modeling - Pharmaco-PET/MR to Predict Antidepressant Drug Efficacy
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中(未招募)
- 入组人数
- 195
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •General health based on medical history, physical examination and structured clinical interview for DSM-IV (SCID)
- •Age 18 to 55 years
- •HAM-D >17 (MDD patients)
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 195
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Any medical, psychiatric or neurological illness (other than MDD)
- •Psychopharmacological treatment within 3 months prior to inclusion (excepting occasional intake of antihistamines and benzodiazepines, given a wash-out of at least one day prior to PET/MR measurements)
- •Current or former substance abuse (excepting nicotine)
- •Any implant or stainless steel graft or any other contraindications for MRI
- •Participation in studies involving radiation exposure in the past 10 years.
- •Body mass index <17 or >30
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