Simvastatin effect on orthodontic relapse
Phase 2
- Conditions
- orthodontic relapse.Fitting and adjustment of orthodontic device
- Registration Number
- IRCT2013041813054N1
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 24
Inclusion Criteria
Female patients with 20 to 45 years old, with 4 to 6 mm space between front teeth of upper or lower gingival, controlled chronic periodontitis with Clinical Attachment Loss of 4 to 6 mm and without known allergy to simvastatin group medicines. Big tongue was not the cause of space.
Exclusion criteria: Patients under systemic therapy with simvastatin group medicines, pregnant or breath feeding patients, sever periodontitis patients, smoker or alcoholic patients, patients with diabetes or immunosuppressive diseases.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gingival index. Timepoint: Before the study and eight weeks after injection in control and intervention group. Method of measurement: According to bleeding index.;Clinical Attachment Loss. Timepoint: Before the study and eight weeks after injection in control and intervention group. Method of measurement: By Probe.
- Secondary Outcome Measures
Name Time Method