An Observational Longitudinal Study to Explore the Concordance between an Advanced Generative AI Model, Live Clinical Prescription, and a Gold Standard Prescription of Drug Appropriateness, Dosing, and Drug-Drug Interactions in a Medical ICU.

Short Description / Primary Purpose & Hypothesis

This study aims to compare prescriptions generated by an advanced generative AI model with live clinician prescriptions and gold standard prescriptions in a Medical ICU. The primary purpose is to evaluate concordance in drug appropriateness, dosing, and identification of drug–drug interactions.

Hypothesis: AI-assisted prescription review will reduce inappropriate drugs, clinically significant drug–drug interactions, and dosing errors compared to conventional clinician-driven prescriptions, thereby improving medication safety.