A Phase 1 Study of SGN-ALPV in Advanced Solid Tumors

Phase 1

• Conditions: gastroesophageal junction [GEJ] carcinoma, Non-small cell lung cancer (NSCLC), Gastric cancer, Cervical cancer, Ovarian cancer, Endometrial cancer, Malignant ovarian GCT with the exception of pure teratomas, Malignant testicular germ cell tumor (GCT) with the exception of pure teratomas, Gastroesophageal junction carcinoma, Malignant extragonadal GCT with the exception of pure teratomas or tumors with primaries arising from the central nervous system (CNS); MedDRA version: 21.1Level: LLTClassification code: 10043338Term: Testicular malignant germ cell tumor NOS Class: 10029104; MedDRA version: 21.1Level: PTClassification code: 10017758Term: Gastric cancer Class: 100000004864; MedDRA version: 21.1Level: PTClassification code: 10061873Term: Non-small cell lung cancer Class: 100000004864; MedDRA version: 20.0Level: HLTClassification code: 10033222Term: Ovarian germ cell neoplasms malignant Class: 10029104; MedDRA version: 21.1Level: LLTClassification code: 10008229Term: Cervical cancer Class: 10029104; MedDRA version: 21.0Level: PTClassification code: 10014733Term: Endometrial cancer Class: 100000004864; MedDRA version: 21.1Level: LLTClassification code: 10066354Term: Adenocarcinoma of the gastroesophageal junction Class: 10029104; MedDRA version: 20.0Level: PTClassification code: 10033128Term: Ovarian cancer Class: 100000004864; MedDRA version: 20.0Level: LLTClassification code: 10073060Term: Extragonadal primary germ cell tumor Class: 10029104

• Registration Number: CTIS2022-500094-14-00
• Lead Sponsor: Seagen Inc.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-31
• Study Completion: 2023-12-13
• Last Update Posted: 21 August 2024

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: 254

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: ;Secondary Objective: ;Primary end point(s):