autologous platelet rich plasma for Ovarian rejuvenatio

Not Applicable

Conditions: Health Condition 1: N978- Female infertility of other origin

Registration Number: CTRI/2023/05/053123

Lead Sponsor: VMMC and Safdarjung hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

Serum AMH (Anti Mullerian Hormone)<=1.2/ml,

AFC (Antral Follicle Count) < 5(Follicles between 2-9 mm assessed sonographically on day 2/3 of periods),

Serum FSH(Follicle Stimulating Hormone) > 12,

Hb >11 gm% and platelets >1.5 lakhs.

Exclusion Criteria

previous history of Pelvic Inflammatory Disease (PID), Suspected pelvic adhesions, known clinical/biochemical hyperandrogenism or PCOS, Severe male factor infertility, history of symptoms of platelet dysfunction such as easy bruisability, frequent nose-bleeds, heavy menstrual bleeding, bleeding gums or excessive bleeding during dental procedures ,blood borne disease like Hepatitis B, Hepatitis C, Syphilis, HIV, NSAIDs intake in 10 days before the procedure ,patient on anticoagulant therapy, mullerian abnormality, Ashermann Syndrome, moderate /severe endometriosis, active vaginal/cervix infection, any significant co-morbidity/ psychiatric disorder which compromise or interfere with consent giving/study participation/ follow up or interpretation of study.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Antral Follicle Count (defined as all follicles of 2-9 mm on day 2 scan on TVS), <br/ ><br>2.Serum AMH <br/ ><br>3.Serum FSH at the end of the treatment cycle. <br/ ><br>Timepoint: 3 months

Secondary Outcome Measures