Effects of tDCS and tRNS on attention and pain in multiple sclerosis

Not Applicable

• Conditions: G35; Multiple sclerosis

• Registration Number: DRKS00005296
• Lead Sponsor: Association ANTALGOCentre Hospitalier Nemours

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-09-11
• Study Completion: 2013-12-18
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

multiple sclerosis; all subtypes; patients with and without pain

Exclusion Criteria

other neurologic disorders, severe internal disorders, lack of informed consent, metal implants, seizures in medical history

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Completion of the study after 9 weeks: (I) significant improvement of attention, proven by a lower failure rate in the attention network test and (II) significant attenuation of pain related evoked potentials in the EEG after active tDCS and tRNS compared to sham stimulation.

Secondary Outcome Measures

Name	Time	Method
Completion of the study after 9 weeks: (I) Significant improvement of depression rating in the Hospital Anxiety ans Depression Scale (HADS) and the Modified Fatigue Impact Scale (MFIS) and (II) significant reduction in pain perception in the Brief Pain Inventory (BPI) after active tDCS and tRNS compared to sham stimulation.