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Clinical Trials/CTRI/2025/07/090995
CTRI/2025/07/090995
Completed
Phase 4

External Oblique Intercoastal Plane Block Versus Erector Spinae Plane Block for Post Operative Analgesia in Donor Hepatectomy Patients- A Randomized Control Trial

Institute of Liver and Biliary Sciences1 site in 1 country60 target enrollmentStarted: July 26, 2025Last updated:

Overview

Phase
Phase 4
Status
Completed
Enrollment
60
Locations
1
Primary Endpoint
To compare the total amount of postoperative rescue analgesia (IV fentanyl) requirement during first 24hrs in External Oblique Intercoastal block and Erector Spinae Plane block groups

Overview

Brief Summary

Ultrasound guided External Oblique intercoastal Plane block is a emerging technique, which blocks anterior and lateral cutaneous branches of thoracoabdominal nerves and has been successful in upper abdominal surgeries for perioperative pain management. Erector spinae plane block have been in practice for some time for thoracic surgeries and major abdominal surgeries. As there is no literature comparing both the blocks  in donor hepatectomy surgeries, this study will compare both the blocks for perioperative analgesia in patient undergoing donor hepatectomy surgeries.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant and Outcome Assessor Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • ASA 1 & 2 patients undergoing donor hepatectomy surgery
  • Donor hepatectomy surgery.

Exclusion Criteria

  • Patient refusal
  • Infection at site of administration
  • Allergy to local anaesthetics
  • Insufficient comprehension to use of PCA.

Outcomes

Primary Outcomes

To compare the total amount of postoperative rescue analgesia (IV fentanyl) requirement during first 24hrs in External Oblique Intercoastal block and Erector Spinae Plane block groups

Time Frame: at 24 hours

Secondary Outcomes

  • 1. To compare the intraoperative IV fentanyl requirements in both the groups(2. To compare the time of first rescue analgesia requirement in both the groups)

Investigators

Sponsor Class
Research institution and hospital
Responsible Party
Principal Investigator
Principal Investigator

Savita Agarwal

Institute of Liver and Biliary Sciences

Study Sites (1)

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