sing melatonin pill to reduce the risk of cancer due to exposure to radiation doses from CT imaging .
Phase 3
Recruiting
- Conditions
- .....
- Registration Number
- IRCT20171122037593N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
healthy person
non-athlete
non-smoker
non-alcoholic
no-radiation therapy
no- history of chemotherapy
Exclusion Criteria
smoker
alcoholic
having radiation therapy
having chemotherapy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gamma-h2ax foci per cell that represent double strand break( DSB) in cell. Timepoint: Counting the number of DSB in the control group at zero time without taking melatonin and also 1 hour before radiation. Method of measurement: Using the immune fluorescence assay, using gamma-h2ax antibodies and fluorescence microscopy, the number of gamma-h2ax foci is counted.
- Secondary Outcome Measures
Name Time Method