Biomarkers for disease activity of juvenile idiopathic arthritis
Completed
- Conditions
- Childhood ArthritisJuvenile Idiopathic Arthritis1000381610023213
- Registration Number
- NL-OMON42570
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
Clinically suspected JIA or diagnosed with JIA.
Scheduled to undergo MRI of the affected joint.
Written informed patients (when >12 years of age) and parental consent
OR
JIA patients with clinically inactive disease for at least 6 months.
A history of clinical evident arthritis in at least 1 joint.
Scheduled to undergo MRI of knee, hand/wrist, ankle or SI joint.
Written informed patients (when >12 years of age) and parental consent.
Exclusion Criteria
Age <8 and >18 years.
General contraindications for MRI (such as renal insufficiency, pregnancy and claustrophobia)
Lack of written informed consent
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The accuracy, validity, correlation, predictive value and responsiveness to<br /><br>change of physical examination, imaging and biomarkers for the clinical course<br /><br>in JIA patients. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The construction of a prediction model in JIA disease activity<br /><br>The evaluation of high resolution, 3.0T MRI characteristics in the different<br /><br>JIA subtypes </p><br>