Family Based Contingency Management for Adolescent Alcohol Abuse
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 75
- 试验地点
- 2
- 主要终点
- Alcohol Abstinence
研究概览
简要总结
The goal is to adapt the family-based CM treatment to target primary adolescent alcohol abuse and dependence.
Specific Aim 1 is to provide a preliminary demonstration of the efficacy of a family-based CM intervention to treat adolescent alcohol abuse and dependence. CM components include:
- an incentive program to enhance the adolescent's engagement in the treatment process and engender alcohol abstinence by providing positive reinforcement for documented abstinence via breathalyzers administered by parents regularly at home, self and parent report, and clinic-based urine drug testing; and
- a parent management training program to enhance and maintain the positive effects of the incentive program by teaching parents how to effectively use contingency management in the home environment to motivate their adolescent to achieve abstinence and improve their behavior in other domains.
A randomized trial will determine whether the CM intervention enhances outcomes when added to a standard individual cognitive behavioral therapy (CBT).
Specific Aim 2 is to determine whether and how treatment interventions modify parental and adolescent risk and protective factors using observational and laboratory measures (parenting practices, family functioning, risk taking, delay discounting, and child and parent psychopathology) and to determine whether these factors are associated with outcomes over time.
Specific Aim 3 is to test gene x environment (treatment) interactions in adolescent substance abuse. Findings will extend the scientific evidence for CM and support the ability of parents to implement CM at home. Findings that support the CM model's efficacy will make a significant contribution to research on the treatment of adolescent alcohol abuse, which has lagged behind research on adult substance abuse and on adolescent illicit drug use.
详细描述
Approximately 1.5 million youth ages 12-17 (representing 6.1% of all youth in that age range) are in need of treatment for alcohol abuse, yet only 7.2% of those in need of treatment received it. Importantly, most youth (90.5%) who were classified as needing treatment based on their self report of Adolescent Alcohol Study Plan; v.2; 3/30/12Page 2 of 35 symptoms, perceived no need for treatment. Thus, there is a need to develop treatments that target populations of alcohol abusing youth who are not highly motivated to change their substance use. New outpatient family based and contingency management interventions for adolescent marijuana abuse have been developed, yet none of these interventions has specifically targeted adolescent alcohol use. It is important to target primary alcohol abuse and dependence in adolescence as approximately 20% of treatment-seeking youth report primary problems with alcohol. The primary aim of this proposal is to adapt our family-based contingency-management treatment to target adolescent alcohol abuse and dependence. This project will develop, manualize, and pilot a contingency management intervention that includes two components. First, an incentive program will enhance the adolescent's engagement in the treatment process and engender alcohol abstinence by providing positive reinforcement for documented abstinence via breathalyzers administered by parents regularly at home, self and parent report, and clinic based urine drug testing. Second, a parent management training program will enhance and maintain the positive effects of the incentive program by teaching parents how to effectively use contingency management in the home environment to motivate their adolescent to achieve abstinence and improve their behavior in other domains.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 12 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •12-18 years old (if 18, must attend high school and live at home)
- •Report using alcohol during the previous 30 days
- •Have a parent/guardian who can participate
- •Meet DSM criteria for either Alcohol Abuse or Dependence
- •Youth who meet DSM criteria for Alcohol Dependence may also meet criteria for Marijuana Abuse or Dependence and other Drug Abuse
- •Youth who meet DSM criteria for Alcohol Abuse, may also meet criteria for Marijuana or other Drug Abuse
- •Live within a 30-minute drive of the clinic
排除标准
- •Meet DSM criteria for Drug Dependence (other than Marijuana Dependence)
- •Meet DSM criteria for Alcohol Abuse with Marijuana Dependence. Use of other drugs will not be excluded
- •Participants will also be excluded if they exhibit an active psychosis
- •Have a severe medical or psychiatric illness that will limit participation
- •Are pregnant or breast-feeding
研究组 & 干预措施
1
Motivational Enhancement Therapy (MET)/CBT+CM/BPT
干预措施: Motivational Enhancement Therapy (MET)/CBT+CM (Behavioral)
2
Motivational Enhancement Therapy (MET)/CBT
干预措施: Motivational Enhancement Therapy (MET)/CBT (Behavioral)
结局指标
主要结局
Alcohol Abstinence
时间窗: Weekly up to 14 weeks
Number of non-abstinent urinalysis (ETG-positive) samples during 14 weeks of treatment (considering missing samples as non-abstinent)
次要结局
- Days of Alcohol Use During 36-week Follow-up Period(Monthly up to 9 months (36 weeks))
研究者
Catherine Stanger
Associate Professor
Dartmouth-Hitchcock Medical Center