“A Randomized Open Labelled Controlled ClinicalStudy To Evaluate The Efficacy Of Swarnapatri (Cassiaangustifolia) Kashaya Parisheka In Amavata
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Reduction of Warmth of the joints.
研究概览
简要总结
Amavata is one of the dreaded diseases that the mankind faces today. Even though Amavata is not proved to be fatal, it cripples the affected patients. It can affect many facets ofa patient’s life, viz. his family, occupational and community relationships even. As far as symptomatology is concerned, rheumatoid arthritis and Amavata are having similarities. Amavata presents with the cardinal symptoms like gaurava and vruschika damshavat vedana1. In recent years an intense study of different conditions primarily involving the musculoskeletal structures (rheumatology) has been made and it revealed that inflammatory or degenerative changes2 occur in disease like R.A. So, recent scholars are trying to co-relate Amavata with rheumatoid arthritis. Rheumatoid arthritis occurs throughout the world and in all ethnic groups3. The overall prevalence of rheumatoid arthritis is 0.8% of the total world population. In India, the incidence of Amavata (rheumatoid Arthritis) is reported to be 1-2% of general population with a female to male ratio4 of 3:1.In chikitsa sutra of Amavata, swedana is one of the lines of treatment5 . Swedanabecause of ushna guna acts on sheeta guna of vata and kapha, which in turn mitigates vata and kapha dosha6 . Parisheka is one of the varieties of sweda. Swarnapatri, Cassia angustifolia which is having ruksha guna and vata-kapha hara actions7 are widely used in traditional Chinese medicine, and has anti-inflammatory activity8, it is useful in relieving people from the condition of osteoarthritis, gout and rheumatoid arthritis9, and hence swarnapatri is selected.Till date there is no satisfactory modern medical management for pain and stiffness developed for this disease. Therefore patients are continuously looking with hope towards Ayurveda to overcome the challenge. By considering the pathogenesis and samprapti ghatakas of Amavata, this research aim to know whether adopting sarvanga parisheka sweda with swarnapatri kashaya will help in reduction in the pain and stiffness caused by Amavata.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 21.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Subjects fit for kayaseka and ruksha sweda.
- •Subjects who satisfy 6 criteria out of 10 of ACR.
- •Subjects with classical signs and symptoms of Amavata.
- •Those who are willing to give informed consent.
排除标准
- •â€¢ Subjects suffering from Rheumatoid arthritis secondary to any systemic diseases.
- •â€¢ Subjects on any other medications like NSAID, corticosteroids.
- •â€¢ Pregnant women and lactating mother.
- •â€¢ Subjects having complications like swan neck deformity, ulnar deviation and any other diseases which interfere with the course of disease and treatment will be excluded.
结局指标
主要结局
Reduction of Warmth of the joints.
时间窗: 22 days
Swelling of the joints.
时间窗: 22 days
Reduction in Stiffness of the joints.
时间窗: 22 days
Reduction in Tenderness of the joints.
时间窗: 22 days
次要结局
- Reduction of Pain in the multiple joints and in small joints .(Reduction of Morning stiffness which lasts at least an hour.)