The effectiveness of dexmedetomidine on pain relief after unilateral total knee arthroplasty
Phase 2
- Conditions
- nilateral total knee arthroplasty.Presence of orthopaedic joint implantsZ96.6
- Registration Number
- IRCT20230215057432N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
Patients candidate for unilateral total knee arthroplasty
Age over 18 years
Exclusion Criteria
Having a contraindication for adductor canal block
Having diabetes mellitus
Having local anesthetics allergies
Bradycardia
Long-term use of analgesics
Having liver failure
Having renal failure
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of pain. Timepoint: 1, 3, 6, 12, 18 and 24 hours after intervention. Method of measurement: Visual analogue scale (VAS).
- Secondary Outcome Measures
Name Time Method The rate of pain reliever consumption. Timepoint: 24 hours after intervention. Method of measurement: Type and amount of pain reliever consumed by the patient.;Prescribing the first pain reliever after surgery. Timepoint: After intervention. Method of measurement: Based on minutes after surgery.;100-step walking test time. Timepoint: Before, one and two days after intervention. Method of measurement: Based on minutes.