TCTR20210729002已完成不适用
Clinical Parameters and Biological Markers associated with Acute Severe Ocular Complications in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Thailand
Ratchadapisek Sompoch Endowment Fund0 个研究点目标入组 47 人开始时间: 2021年7月29日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 47
研究概览
简要总结
The disease (TEN or SJS) and older age were predicting factors for acute SOCs in SJS/TEN. - The S100A8/A9 and granulysin levels tended to increase in the severe ocular involvement group, suggesting that S100A8/A9 and granulysin might involve in the pathogenesis of severe ocular involvement and serve as a helpful biomarker to evaluate SOCs in acute SJS/TEN.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 90 Years（—）
- 性别
- All
入选标准
- •1. Patients in Thai SCARs database (dermatological diagnosis of SJS or TEN or SJS-TEN overlap) with ocular involvement
- •2. The patients had medical records of the acute phase, which were fully accessible to evaluate prognostic factors
- •3. The patients did not have a history of other ocular surface disorder or ocular surgery
排除标准
- •1. Clinical information was insufficient to calculate the SCORTEN
- •2. Sepsis (in serum analysis)
- •3. Positive blood culture (in serum analysis)
研究者
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