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Clinical Trials/NCT06660914
NCT06660914
Recruiting
N/A

A Randomized Controlled Trial Comparing Robotic Flexible Ureteroscopy With Standard Flexible Ureteroscopy for Treatment of Renal Stones - A Pilot Study

Chinese University of Hong Kong1 site in 1 country30 target enrollmentDecember 1, 2024
ConditionsRenal Stone

Overview

Phase
N/A
Intervention
Not specified
Conditions
Renal Stone
Sponsor
Chinese University of Hong Kong
Enrollment
30
Locations
1
Primary Endpoint
Stone-free rate at 1 month
Status
Recruiting
Last Updated
12 months ago

Overview

Brief Summary

This is a prospective randomized clinical trial which aims to compare the clinical outcomes of robotic flexible ureteroscopy and standard flexible ureteroscopy for the treatment of renal stones.

Detailed Description

This is a prospective randomized controlled trial comparing robotic flexible ureteroscopy and standard flexible ureteroscopy for patients with treatment of renal stones. All consecutive patients who are scheduled for flexible ureteroscopy for treatment of renal stones would be screened for study eligibility. Patients are randomised to receive either robotic or standard flexible ureteroscopy with an allocation ratio of 1:1. by computer generated random block. The urologist performing the surgery could not be blinded due to the nature of the intervention. Patients receiving the treatment and investigators assessing for any disease recurrence are blinded from the allocated treatment arm.

Registry
clinicaltrials.gov
Start Date
December 1, 2024
End Date
March 3, 2026
Last Updated
12 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

NG Chi Fai

Professor

Chinese University of Hong Kong

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 years old with informed consent
  • Being willing and able to provide written informed consent

Exclusion Criteria

  • Patients with abnormal urinary tract (e.g. ileal conduit, neobladder, ureteric stricture)
  • American Society of Anesthesiologists (ASA) physical status classification system \>3
  • Untreated urinary tract infection
  • Renal stones \> 3cm in diameter

Outcomes

Primary Outcomes

Stone-free rate at 1 month

Time Frame: Month 1

Stone-free rate at 1 month is defined by non contrast computer tomography (NCCT) performed within 24 hours of surgery without residual stone fragments or residual stone fragments \<2mm

Secondary Outcomes

  • Stone-free rate at 3 month(Month 3)
  • Operative time(During operation)
  • Lasing Time(During operation)
  • Total laser energy used(During operation)
  • Total radiation dose(During operation)
  • Total radiation time(during operation)
  • Length of hospital stay(On Discharge)
  • Postoperative pain(Baseline, Week 1 and Week 12)
  • Surgeon radiation exposure(During operation)

Study Sites (1)

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