The Impact of Real-Time Physiological Status Based Pacing Guidance on Physiological Strain for Exercising Humans
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- Physiological Strain Index (PSI)
研究概览
简要总结
The objectives of this study are to demonstrate that real time physiological status monitoring and the use of optimization techniques during exercise can have a positive impact on physiological status, and to collect metabolic flexibility profiles of young fit adults during rest and exercise.
详细描述
This experiment aims to accomplish two goals: collect additional metabolic flexibility data with young fit adults in response to exercise; and demonstrate that automated pace guidance generated from real-time thermal-work strain monitoring and an optimized pacing policy will allow less stressful completion of a timed (60 minute) treadmill exercise of 5 miles. Each participant will undergo two treatments of first UNGUIDED followed by GUIDED exercise. The two exercise sessions will be conducted as part of a ~24 hour stay in an indirect calorimetry chamber.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 29 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male and Female
- •Ages 18 to 29 at the beginning of the study
- •Relatively fit can run 2 miles in under 16 minutes
排除标准
- •History of Skin Sensitivity to Nickel
- •Hypertension
- •Alcoholism
- •Cannot run 2 miles in less than 16 minutes
- •No regular weekly exercise
- •Difficulty Swallowing Food or Large Pills
- •Diverticulitis
- •Inflammatory Bowel Disease
- •Peptic Ulcer Disease
- •Crohn's Disease
- •Ulcerative Colitis
- •Previous Gastrointestinal Surgery
- •Possible Nuclear Magnetic Resonance Scan
- •Women who have given birth during the previous 12 months
- •Pregnant women or women who plan to become pregnant or become pregnant during the study
- •Lactating women
- •History or presence of kidney disease, liver disease, certain cancers, gastrointestinal, pancreatic, other metabolic diseases, or malabsorption syndromes
- •History of bariatric or certain other surgeries related to weight control
- •Smokers or other tobacco users (for at least 6 months prior to the start of the study)
- •History of eating disorders or other dietary patterns which are not consistent with the dietary intervention (e.g., vegetarians, very low fat diets, high protein diets)
- •Volunteers who have lost 10% of body weight within the last 12 months or who plan to initiate a weight loss program during the next 10 months
- •Unable or unwilling to give informed consent or communicate with study staff.
- •Self-report of alcohol or substance abuse within the past 12 months and/or current acute treatment or rehabilitation program for these problems (long-term participation in Alcoholics Anonymous is not an exclusion)
- •Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol
- •Blood donation within the previous month
结局指标
主要结局
Physiological Strain Index (PSI)
时间窗: During 2-hour exercise session
The PSI is an index that combines heart rate and core body temperatures with equal weights into an index from 0 to 10+. PSI will be calculated according to Moran et al. (1998) from measures of heart rate and core body temperature.
次要结局
- Continuous Glucose Monitoring(24 hours)
- Perceived Exertion Scale(During 2-hour exercise session)
- Self Perception Scales(During 2-hour exercise session)
- Metabolic Flexibility(24 hours)
- Feeling Scale(During 2-hour exercise session)
- Profile of Mood States (POMS) Questionnaire(During 2-hour exercise session)
- Motivation(During 2-hour exercise session)
- Thermal Sensation Scale(During 2-hour exercise session)
研究者
William Rumpler
Resesarch Physiologist
USDA Beltsville Human Nutrition Research Center